Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model.

Tumor hypoxia is relevant for tumor growth, metabolism and epithelial-to-mesenchymal transition (EMT). We report that hyperbaric oxygen (HBO) treatment induced mesenchymal-to-epithelial transition (MET) in a dimethyl-alpha-benzantracene induced mammary rat adenocarcinoma model, and the MET was assoc...

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Bibliographic Details
Main Authors: Ingrid Moen, Anne Margrete Øyan, Karl-Henning Kalland, Karl Johan Tronstad, Lars Andreas Akslen, Martha Chekenya, Per Øystein Sakariassen, Rolf Kåre Reed, Linda Elin Birkhaug Stuhr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2712688?pdf=render