An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

Abstract Background Streptococcus pyogenes causes a profound global burden of morbidity and mortality across its diverse clinical spectrum. To support a new controlled human infection (‘challenge’) model seeking to accelerate S. pyogenes vaccine development, we aimed to develop an accurate and relia...

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Bibliographic Details
Main Authors: Loraine V. Fabri, Kristy I. Azzopardi, Joshua Osowicki, Hannah R. Frost, Pierre R. Smeesters, Andrew C. Steer
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Infectious Diseases
Subjects:
Pharyngitis
Human challenge study
qPCR
Nucleic acid extraction
Streptococcus pyogenes
Online Access:https://doi.org/10.1186/s12879-021-06173-w

Internet

https://doi.org/10.1186/s12879-021-06173-w

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