An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis
Abstract Background Streptococcus pyogenes causes a profound global burden of morbidity and mortality across its diverse clinical spectrum. To support a new controlled human infection (‘challenge’) model seeking to accelerate S. pyogenes vaccine development, we aimed to develop an accurate and relia...
Main Authors: | Loraine V. Fabri, Kristy I. Azzopardi, Joshua Osowicki, Hannah R. Frost, Pierre R. Smeesters, Andrew C. Steer |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | BMC Infectious Diseases |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12879-021-06173-w |
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