Comparison of REST cistromes across human cell types reveals common and context-specific functions.

Recent studies have shown that the transcriptional functions of REST are much broader than repressing neuronal genes in non-neuronal systems. Whether REST occupies similar chromatin regions in different cell types and how it interacts with other transcriptional regulators to execute its functions in...

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Bibliographic Details
Main Authors: Shira Rockowitz, Wen-Hui Lien, Erika Pedrosa, Gang Wei, Mingyan Lin, Keji Zhao, Herbert M Lachman, Elaine Fuchs, Deyou Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4055426?pdf=render