Personalized‐induced neural stem cell therapy: Generation, transplant, and safety in a large animal model

Abstract In this study, we take an important step toward clinical translation by generating the first canine‐induced neural stem cells (iNSCs). We explore key aspects of scale‐up, persistence, and safety of personalized iNSC therapy in autologous canine surgery models. iNSCs are a promising new appr...

Full description

Bibliographic Details
Main Authors: Hunter N. Bomba, Kevin T. Sheets, Alain Valdivia, Simon Khagi, Laura Ruterbories, Christopher L. Mariani, Luke B. Borst, Debra A. Tokarz, Shawn D. Hingtgen
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10171