Novel Multifunctional Ascorbic Triazole Derivatives for Amyloidogenic Pathway Inhibition, Anti-Inflammation, and Neuroprotection

Novel Multifunctional Ascorbic Triazole Derivatives for Amyloidogenic Pathway Inhibition, Anti-Inflammation, and Neuroprotection

Alzheimer’s disease (AD) is a common neurodegenerative disorder. The number of patients with AD is projected to reach 152 million by 2050. Donepezil, rivastigmine, galantamine, and memantine are the only four drugs currently approved by the United States Food and Drug Administration for AD treatment...

Full description

Bibliographic Details
Main Authors: Jutamas Jiaranaikulwanitch, Hataichanok Pandith, Sarin Tadtong, Phanit Thammarat, Supat Jiranusornkul, Nattapong Chauthong, Supitcha Nilkosol, Opa Vajragupta
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
ascorbic derivatives
BACE1 inhibitor
amyloid aggregation inhibition
antioxidant
neuroprotective
anti-inflammation
Online Access:https://www.mdpi.com/1420-3049/26/6/1562

Internet

https://www.mdpi.com/1420-3049/26/6/1562

Similar Items