The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Epigenetic factors (EFs) regulate multiple aspects of cerebral cortex development, including proliferation, differentiation, laminar fate, and regional identity. The same neurodevelopmental processes are also regulated by transcription factors (TFs), notably the Pax6→ Tbr2→ Tbr1 cascade expressed se...

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Bibliographic Details
Main Authors: Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neuroscience
Subjects:
cortical development
polycomb
BAF
NuRD
histone acetylation
lncRNA
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00571/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00571/full

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