The dual effect of cannabinoid receptor-1 deficiency on the murine postoperative ileus.

INTRODUCTION: Intestinal inflammatory responses play a critical role in the pathogenesis of postoperative ileus (POI). As cannabinoid receptor-1 (CB1) is involved in inhibiting gastrointestinal (GI) motility and anti-inflammation, we aimed to explore its contribution to POI. METHODS: Experimental PO...

Full description

Bibliographic Details
Main Authors: Yong-yu Li, Ming-hua Cao, Brigitte Goetz, Chun-qiu Chen, Ya-jing Feng, Chang-Jie Chen, Michael S Kasparek, Andrej Sibaev, Martin Storr, Martin E Kreis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701010?pdf=render