BMP4 acts as a dorsal telencephalic morphogen in a mouse embryonic stem cell culture system

The concept of a morphogen – a molecule that specifies two or more cell fates in a concentration-dependent manner – is paradigmatic in developmental biology. Much remains unknown, however, about the existence of morphogens in the developing vertebrate central nervous system (CNS), including the mous...

Full description

Bibliographic Details
Main Authors: Momoko Watanabe, Ernest S. Fung, Felicia B. Chan, Jessica S. Wong, Margaret Coutts, Edwin S. Monuki
Format: Article
Language:English
Published: The Company of Biologists 2016-12-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/5/12/1834