Modeling the amplification dynamics of human Alu retrotransposons.

Retrotransposons have had a considerable impact on the overall architecture of the human genome. Currently, there are three lineages of retrotransposons (Alu, L1, and SVA) that are believed to be actively replicating in humans. While estimates of their copy number, sequence diversity, and levels of...

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Bibliographic Details
Main Authors: Dale J Hedges, Richard Cordaux, Jinchuan Xing, David J Witherspoon, Alan R Rogers, Lynn B Jorde, Mark A Batzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1239904?pdf=render