Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.

Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.

We have previously reported radiation-induced sensitization of canine osteosarcoma (OSA) to natural killer (NK) therapy, including results from a first-in-dog clinical trial. Here, we report correlative analyses of blood and tissue specimens for signals of immune activation in trial subjects. Among...

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Bibliographic Details
Main Authors: Sean J Judge, Mio Yanagisawa, Ian R Sturgill, Sarah B Bateni, Alicia A Gingrich, Jennifer A Foltz, Dean A Lee, Jaime F Modiano, Arta M Monjazeb, William T N Culp, Robert B Rebhun, William J Murphy, Michael S Kent, Robert J Canter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224775

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https://doi.org/10.1371/journal.pone.0224775

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