Disruption of the white matter structural network and its correlation with baseline progression rate in patients with sporadic amyotrophic lateral sclerosis

Abstract Objective There is increasing evidence that amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease impacting large-scale brain networks. However, it is still unclear which structural networks are associated with the disease and whether the network connectomics are as...

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Bibliographic Details
Main Authors: Wenbin Li, Qianqian Wei, Yanbing Hou, Du Lei, Yuan Ai, Kun Qin, Jing Yang, Graham J. Kemp, Huifang Shang, Qiyong Gong
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Translational Neurodegeneration
Subjects:
DTI
Online Access:https://doi.org/10.1186/s40035-021-00255-0