Thioredoxin 80-activated-monocytes (TAMs) inhibit the replication of intracellular pathogens.

<h4>Background</h4>Thioredoxin 80 (Trx80) is an 80 amino acid natural cleavage product of Trx, produced primarily by monocytes. Trx80 induces differentiation of human monocytes into a novel cell type, named Trx80-activated-monocytes (TAMs).<h4>Principal findings</h4>In this i...

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Main Authors: Ximena Cortes-Bratti, Eugénie Bassères, Fabiola Herrera-Rodriguez, Silvia Botero-Kleiven, Giuseppe Coppotelli, Jens B Andersen, Maria G Masucci, Arne Holmgren, Esteban Chaves-Olarte, Teresa Frisan, Javier Avila-Cariño
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21365006/?tool=EBI