DNA gyrase could be a crucial regulatory factor for growth and survival of Mycobacterium leprae
Abstract Leprosy, an important infectious disease in humans caused by Mycobacterium leprae (Mle), remains endemic in many countries. Notably, the pathogen cannot be cultured in vitro, except in mouse footpads in vivo. The molecular basis of these characteristics and the mechanisms remain unknown. Co...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-47364-5 |