Review and Hypothesis: A Potential Common Link Between Glial Cells, Calcium Changes, Modulation of Synaptic Transmission, Spreading Depression, Migraine, and Epilepsy—H+

There is significant evidence to support the notion that glial cells can modulate the strength of synaptic connections between nerve cells, and it has further been suggested that alterations in intracellular calcium are likely to play a key role in this process. However, the molecular mechanism(s) b...

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Bibliographic Details
Main Authors: Robert Paul Malchow, Boriana K. Tchernookova, Ji-in Vivien Choi, Peter J. S. Smith, Richard H. Kramer, Matthew A. Kreitzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
pH
H+
ATP
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.693095/full