Dendrobium nobile Lindl. alkaloids alleviate Mn-induced neurotoxicity via PINK1/Parkin-mediated mitophagy in PC12 cells

Dendrobium nobile Lindl. alkaloids alleviate Mn-induced neurotoxicity via PINK1/Parkin-mediated mitophagy in PC12 cells

Modern pharmacological studies have demonstrated that Dendrobium nobile Lindl. Alkaloids (DNLA), the main active ingredients of Dendrobium nobile, is valuable as an anti-aging and neuroprotective herbal medicine. The present study was designed to determine whether DNLA confers protective function ov...

Full description

Bibliographic Details
Main Authors: Xiaolong Fu, Shu Chen, Xueting Wang, Yanhua Shen, Ru Zeng, Qin Wu, Yuanfu Lu, Jingshan Shi, Shaoyu Zhou
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Manganese
Dendrobium nobile Lindl. alkaloid
Autophagy
PINK1
Parkin
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301874

Internet

http://www.sciencedirect.com/science/article/pii/S2405580820301874

Similar Items