Icariin Ameliorate Thiram-Induced Tibial Dyschondroplasia via Regulation of WNT4 and VEGF Expression in Broiler Chickens

Tibial dyschondroplasia (TD) is main bone problem in fast growing poultry birds that effect proximal growth plate (GP) of tibia bone. TD is broadly defined as non-vascularized and non-mineralized, and enlarged GP with tibia bone deformation and lameness. Icariin (Epimedium sagittatum) is a tradition...

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Bibliographic Details
Main Authors: Hui Zhang, Khalid Mehmood, Kun Li, Mujeeb U. Rehman, Xiong Jiang, Shucheng Huang, Lei Wang, Lihong Zhang, Xiaole Tong, Fazul Nabi, Wangyuan Yao, Muhammad K. Iqbal, Muhammad Shahzad, Jiakui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
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Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00123/full