JAK/STAT guarantees robust neural stem cell differentiation by shutting off biological noise

Abstract Organismal development is precisely regulated by a sequence of gene functions even in the presence of biological noise. However, it is difficult to evaluate the effect of noise in vivo, and the mechanisms by which noise is filtered during development are largely unknown. To identify the noi...

Full description

Bibliographic Details
Main Authors: Yoshitaro Tanaka, Tetsuo Yasugi, Masaharu Nagayama, Makoto Sato, Shin-Ichiro Ei
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-30929-1