Identification of cytolytic CD161- CD56+ regulatory CD8 T cells in human peripheral blood.

We previously developed methods for establishing CD8 regulatory T cell (Treg) clones from normal human peripheral blood and demonstrated that these clones were capable of killing T cell receptor (TCR)-activated autologous CD4 T cells. Based on phenotypic and functional characterization of the CD8 Tr...

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Bibliographic Details
Main Authors: Dan Hu, Howard L Weiner, Jerome Ritz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602421?pdf=render