Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280.

Japanese encephalitis virus (JEV) can cause severe central nervous disease with a high mortality rate. There is no antiviral drug available for JEV-specific treatment. In this study, a cytopathic-effect-based, high-throughput screening assay was developed and applied to screen JEV inhibitors from Li...

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Bibliographic Details
Main Authors: Jin'e Fang, Leqiang Sun, Guiqing Peng, Jia Xu, Rui Zhou, Shengbo Cao, Huanchun Chen, Yunfeng Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3857149?pdf=render