Combined life-threatening thromboses and hemorrhages in a patient with afibrinogenemia and antithrombin deficiency

Abstract Background Patients with congenital afibrinogenemia suffer from spontaneous recurrent severe bleeding. While fibrinogen concentrates are known to effectively treat bleeding episodes, thrombotic complications often occur upon replacement therapy, rendering clinical management highly challeng...

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Bibliographic Details
Main Authors: S. Le Quellec, A. Desjonqueres, L. Rugeri, H. Desmurs Clavel, F. Farhat, L. Mechtouff, Y. Dargaud
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Thrombosis Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12959-018-0162-8