Physiological and pathological phosphorylation of tau by Cdk5
Hyperphosphorylation of microtubule-associated protein tau is one of the major pathological events in Alzheimer’s disease (AD) and other related neurodegenerative diseases, including Frontotemporal Dementia with Parkinsonism linked to chromosome 17 (FTDP-17). Mutations in the tau gene MAPT are a cau...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-07-01
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| Series: | Frontiers in Molecular Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00065/full |