The effect of drug ionization on lipid-based formulations for the oral delivery of anti-psychotics
Lipid-based formulations (LBFs) are well-known to improve the oral bioavailability of poorly water-soluble drugs (PWSDs) by presenting the drug to the gastrointestinal environment in a molecularly dispersed state, thus avoiding the rate-limiting dissolution step. Risperidone and lurasidone are antip...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Association of Physical Chemists (IAPC)
2020-07-01
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| Series: | ADMET and DMPK |
| Online Access: | https://pub.iapchem.org/ojs/index.php/admet/article/view/830 |