Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response

<p>Abstract</p> <p>Background</p> <p>Notch and TLR pathways were found to act cooperatively to activate Notch target genes and to increase the production of TLR-induced cytokines in macrophages. However, the mechanism of LPS-induced Notch activation and its role in seps...

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Bibliographic Details
Main Authors: Chen Chien-Yi, Chou Hung-Chieh, Lee Ming-Cheng, Huang Miao-Tzu, Wei Shu-Chen, Tsao Po-Nien, Hsieh Wu-Shiun
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/18/1/56