In ovo CpG DNA delivery increases innate and adaptive immune cells in respiratory, gastrointestinal and immune systems post-hatch correlating with lower infectious laryngotracheitis virus infection.

Cytosine-guanosine deoxynucleotides (CpG) DNA can be delivered in ovo at embryo day (ED)18 for the stimulation of toll-like receptor (TLR)21 signaling pathway that ultimately protects chickens against a number of bacterial and viral infections. There is a dearth of information understanding the mech...

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Bibliographic Details
Main Authors: Mohamed Sarjoon Abdul-Cader, Aruna Amarasinghe, Victor Palomino-Tapia, Hanaa Ahmed-Hassan, Khawaja Bakhtawar, Eva Nagy, Shayan Sharif, Susantha Gomis, Mohamed Faizal Abdul-Careem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5841808?pdf=render