Effect of Degeneration on Fluid-Solid Interaction within Intervertebral Disc under Cyclic Loading – A Meta-Model Analysis of Finite Element Simulations

Effect of Degeneration on Fluid-Solid Interaction within Intervertebral Disc under Cyclic Loading – A Meta-Model Analysis of Finite Element Simulations

The risk of low back pain resulted from cyclic loadings is greater than that resulted from prolonged static postures. Disc degeneration results in degradation of disc solid structures and decrease of water contents, which is caused by activation of matrix digestive enzymes. The mechanical responses...

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Bibliographic Details
Main Authors: Mohammad eNikkhoo, Kinda eKhalaf, Ya-Wen eKuo, Yu-Chun eHsu, Mohammad eHaghpanahi, Mohamad eParnianpour, Jaw-Lin eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Response Surface Methodology
Poroelastic FE model
Porcine intervertebral disc
Fluid-Solid Interaction
Artificial degeneration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00004/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00004/full

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