Immune Control of Burkholderia pseudomallei––Common, High-Frequency T-Cell Responses to a Broad Repertoire of Immunoprevalent Epitopes

Immune Control of Burkholderia pseudomallei––Common, High-Frequency T-Cell Responses to a Broad Repertoire of Immunoprevalent Epitopes

Burkholderia pseudomallei (Bp) is an environmental bacterial pathogen that causes potentially lethal sepsis in susceptible individuals and is considered a Category B, Tier-1 biothreat agent. As such, it is crucial to gain an improved understanding of protective immunity and potential vaccine candida...

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Bibliographic Details
Main Authors: Arnone Nithichanon, Darawan Rinchai, Surachat Buddhisa, Pornpun Saenmuang, Chidchamai Kewcharoenwong, Bianca Kessler, Prasong Khaenam, Ploenchan Chetchotisakd, Bernard Maillere, John Robinson, Catherine J. Reynolds, Rosemary J. Boyton, Daniel M. Altmann, Ganjana Lertmemongkolchai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
Burkholderia pseudomallei
epitope
T cell
melioidosis
IFNγ
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00484/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00484/full

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