Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

Abstract Background The World Health Organization (WHO) recommends combinations of an artemisinin derivative plus an anti-malarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infections. In Africa, artesunate–mefloquine (ASMQ) is an infrequently used artemis...

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Bibliographic Details
Main Authors: Monia Guidi, Thomas Mercier, Manel Aouri, Laurent A. Decosterd, Chantal Csajka, Bernhards Ogutu, Gwénaëlle Carn, Jean-René Kiechel
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Malaria Journal
Subjects:
Population pharmacokinetics
Mefloquine
Artesunate
Dihydroartemisinin
Online Access:http://link.springer.com/article/10.1186/s12936-019-2754-6

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http://link.springer.com/article/10.1186/s12936-019-2754-6

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