Mutational spectrum of the <it>SPG4 </it>(<it>SPAST</it>) and <it>SPG3A </it>(<it>ATL1</it>) genes in Spanish patients with hereditary spastic paraplegia

Mutational spectrum of the <it>SPG4 </it>(<it>SPAST</it>) and <it>SPG3A </it>(<it>ATL1</it>) genes in Spanish patients with hereditary spastic paraplegia

<p>Abstract</p> <p>Background</p> <p>Hereditary Spastic Paraplegias (HSP) are characterized by progressive spasticity and weakness of the lower limbs. At least 45 loci have been identified in families with autosomal dominant (AD), autosomal recessive (AR), or X-linked h...

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Main Authors: Ribacoba Renne, Moris Germán, de Munain Adolfo, Pascual-Pascual Samuel I, Gonzalo Juan F, Esteban Jesús, Gámez Josep, Corao Ana I, Alonso Belén, Díaz Marta, Beetz Christian, Sánchez-Ferrero Elena, Álvarez Victoria, Márquez Celedonio, Rosell Jordi, Marín Rosario, García-Barcina Maria J, del Castillo Emilia, Benito Carmen, Coto Eliecer
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Neurology
Online Access:http://www.biomedcentral.com/1471-2377/10/89

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http://www.biomedcentral.com/1471-2377/10/89

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