Aflatoxin B1 Induces Neurotoxicity through Reactive Oxygen Species Generation, DNA Damage, Apoptosis, and S-Phase Cell Cycle Arrest

Aflatoxin B1 Induces Neurotoxicity through Reactive Oxygen Species Generation, DNA Damage, Apoptosis, and S-Phase Cell Cycle Arrest

Aflatoxin B1 (AFB<sub>1</sub>) is a mycotoxin widely distributed in a variety of food commodities and exhibits strong toxicity toward multiple tissues and organs. However, little is known about its neurotoxicity and the associated mechanism. In this study, we observed that brain integrit...

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Bibliographic Details
Main Authors: Boyan Huang, Qingmei Chen, Lingling Wang, Xiaojuan Gao, Wenya Zhu, Peiqiang Mu, Yiqun Deng
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
aflatoxin B1
neurotoxicity
reactive oxygen species
DNA damage
cell cycle arrest
apoptosis
Online Access:https://www.mdpi.com/1422-0067/21/18/6517

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https://www.mdpi.com/1422-0067/21/18/6517

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