A novel pathogenic mechanism of highly pathogenic avian influenza H5N1 viruses involves hemagglutinin mediated resistance to serum innate inhibitors.

A novel pathogenic mechanism of highly pathogenic avian influenza H5N1 viruses involves hemagglutinin mediated resistance to serum innate inhibitors.

In this study, the effect of innate serum inhibitors on influenza virus infection was addressed. Seasonal influenza A(H1N1) and A(H3N2), 2009 pandemic A(H1N1) (H1N1pdm) and highly pathogenic avian influenza (HPAI) A(H5N1) viruses were tested with guinea pig sera negative for antibodies against all o...

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Bibliographic Details
Main Authors: Jutatip Panaampon, Nathamon Ngaosuwankul, Ornpreya Suptawiwat, Pirom Noisumdaeng, Kantima Sangsiriwut, Bunpote Siridechadilok, Hatairat Lerdsamran, Prasert Auewarakul, Phisanu Pooruk, Pilaipan Puthavathana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3341361?pdf=render

Internet

http://europepmc.org/articles/PMC3341361?pdf=render

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