Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo.

Functional modulation of the non-AT1R arm of the renin-angiotensin system, such as via AT2R activation, is known to improve stroke outcome. However, the relevance of the Mas receptor, which along with the AT2R forms the protective arm of the renin-angiotensin system, as a target in stroke is unclear...

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Bibliographic Details
Main Authors: Seyoung Lee, Megan A Evans, Hannah X Chu, Hyun Ah Kim, Robert E Widdop, Grant R Drummond, Christopher G Sobey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4634944?pdf=render