Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

The nucleolus is a specialized functional domain of the nucleus where ribosome biogenesis is initiated and also implicated in a p53-dependent anti-tumor surveillance. Here the authors use a quantitative imaging approach to detail the role of each ribosomal protein on the structural integrity of the...

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Bibliographic Details
Main Authors: Emilien Nicolas, Pascaline Parisot, Celina Pinto-Monteiro, Roxane de Walque, Christophe De Vleeschouwer, Denis L. J. Lafontaine
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11390