Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model

Abstract Alzheimer’s disease (AD) is mainly characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent 5xFAD AD mouse model exhibits many AD-related phenotypes and a relatively early and aggressive amyloid β pro...

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Bibliographic Details
Main Authors: Shinwoo Kang, Jinho Kim, Keun-A Chang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79344-5