Suppression of cortical seizures by optic stimulation of the reticular thalamus in PV-mhChR2-YFP BAC transgenic mice

Abstract Deep brain stimulation in thalamic regions has been proposed as a treatment for epilepsy. The electrical current excites thalamocortical activity which is controlled by γ-aminobutyric acid (GABA)ergic interneurons in the reticular thalamic nucleus (nRT). Previous studies showed that enhanci...

Full description

Bibliographic Details
Main Authors: Wei Jen Chang, Wei Pang Chang, Bai Chuang Shyu
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-017-0320-0