Environmental Enrichment Rescues Social Behavioral Deficits and Synaptic Abnormalities in <i>Pten</i> Haploinsufficient Mice

<i>Pten</i> germline haploinsufficient (<i>Pten</i><sup>+/−</sup>) mice, which model macrocephaly/autism syndrome, show social and repetitive behavior deficits, early brain overgrowth, and cortical–subcortical hyperconnectivity. Previous work indicated that altere...

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Bibliographic Details
Main Authors: Amy E. Clipperton-Allen, Angela Zhang, Ori S. Cohen, Damon Theron Page
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/9/1366