Characterization of Tumor-Suppressor Gene Inactivation Events in 33 Cancer Types

Summary: We systematically investigated the landscape of tumor-suppressor gene (TSG) inactivation events in 33 cancer types by quantitatively measuring their global and local genomic features and their transcriptional and signaling footprints. Using The Cancer Genome Atlas data, we identified with h...

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Bibliographic Details
Main Authors: Peilin Jia, Zhongming Zhao
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718320114