CDKN2A/p16INK4a DELETION IS NOT A POOR PROGNOSTIC FACTOR IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS TREATED ACCORDING TO PROTOCOL RALL-2009

Introduction. CDKN2A deletion is a frequent cytogenetic abnormality in acute lymphoblastic leukemia (ALL),  ranging from 18 to 46 %, associating with Т-cell ALL, high WBC counts, splenomegaly, lymphadenopathy. In pediatric group of patient’s CDKN2A deletion was associated with poor event-free surviv...

Full description

Bibliographic Details
Main Authors: I. S. Piskunova, T. N. Obukhova, E. N. Parovichnikova, S. M. Kulikov, O. A. Gavrilina, I. A. Lukyanova, V. G. Savchenko
Format: Article
Language:Russian
Published: ABV-press 2017-10-01
Series:Onkogematologiâ
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/254