Genome Wide Analysis Points towards Subtype-Specific Diseases in Different Genetic Forms of Amyotrophic Lateral Sclerosis

Genome Wide Analysis Points towards Subtype-Specific Diseases in Different Genetic Forms of Amyotrophic Lateral Sclerosis

Amyotropic lateral sclerosis (ALS) is a lethally progressive and irreversible neurodegenerative disease marked by apparent death of motor neurons present in the spinal cord, brain stem and motor cortex. While more and more gene mutants being established for genetic ALS, the vast majority suffer from...

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Bibliographic Details
Main Authors: Banaja P. Dash, Marcel Naumann, Jared Sterneckert, Andreas Hermann
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis (ALS)
human induced pluripotent stem cells (iPSC)
motorneurons (MN)
differentially expressed genes (DEGs)
Kyoto encyclopedia of Genes and Genomes (KEGG)
Online Access:https://www.mdpi.com/1422-0067/21/18/6938

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https://www.mdpi.com/1422-0067/21/18/6938

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