Relationships between Regional Radiation Doses and Cognitive Decline in Children Treated with Cranio-Spinal Irradiation for Posterior Fossa Tumors

Relationships between Regional Radiation Doses and Cognitive Decline in Children Treated with Cranio-Spinal Irradiation for Posterior Fossa Tumors

Pediatric posterior fossa tumor (PFT) survivors who have been treated with cranial radiation therapy often suffer from cognitive impairments that might relate to IQ decline. Radiotherapy (RT) distinctly affects brain regions involved in different cognitive functions. However, the relative contributi...

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Bibliographic Details
Main Authors: Elodie Doger de Speville, Charlotte Robert, Martin Perez-Guevara, Antoine Grigis, Stephanie Bolle, Clemence Pinaud, Christelle Dufour, Anne Beaudré, Virginie Kieffer, Audrey Longaud, Jacques Grill, Dominique Valteau-Couanet, Eric Deutsch, Dimitri Lefkopoulos, Catherine Chiron, Lucie Hertz-Pannier, Marion Noulhiane
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Oncology
Subjects:
pediatric
posterior fossa
radiotherapy
cognitive impairments
radiation effects
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00166/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00166/full

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