Aft2, a novel transcription regulator, is required for iron metabolism, oxidative stress, surface adhesion and hyphal development in Candida albicans.

Aft2, a novel transcription regulator, is required for iron metabolism, oxidative stress, surface adhesion and hyphal development in Candida albicans.

Morphological transition and iron metabolism are closely relevant to Candida albicans pathogenicity and virulence. In our previous study, we demonstrated that C. albicans Aft2 plays an important role in ferric reductase activity and virulence. Here, we further explored the roles of C. albicans Aft2...

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Bibliographic Details
Main Authors: Ning Xu, Xinxin Cheng, Qilin Yu, Kefan Qian, Xiaohui Ding, Ruming Liu, Biao Zhang, Laijun Xing, Mingchun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633901?pdf=render

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http://europepmc.org/articles/PMC3633901?pdf=render

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