Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer

Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer

Abstract The tumour microenvironment is an important factor for colorectal cancer prognosis, affecting the patient's immune response. Immune checkpoints, which regulate the immune functions of lymphocytes, may provide prognostic power. This study aimed to investigate the prognostic value of the...

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Bibliographic Details
Main Authors: Sara SF Al‐Badran, Lauren Grant, Maejoy V Campo, Jitwadee Inthagard, Kathryn Pennel, Jean Quinn, Prakash Konanahalli, Liam Hayman, Paul G Horgan, Donald C McMillan, Campbell SD Roxburgh, Antonia Roseweir, James H Park, Joanne Edwards
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:The Journal of Pathology: Clinical Research
Subjects:
immune checkpoint
TIM‐3
LAG‐3
PD‐1
stromal immune cells
prognosis
Online Access:https://doi.org/10.1002/cjp2.193

Internet

https://doi.org/10.1002/cjp2.193

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