Synthesis and evaluation of cytotoxic activity derived 2,3-diyne-1,4-naphthoquinones

<p>In the present study ten 2,3-diyne-1,4-naphthoquinone derivatives (<strong>3a-j</strong>) were synthesized by Sonogashira coupling reaction between the 2,3-dibromo-1,4-naphthoquinone (<strong>2</strong>) and several functionalized terminal alkynes using a catalytic c...

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Bibliographic Details
Main Authors: Mauro G. da Silva, Tania M. S. Silva, Celso de A. Camara, Anderson C. S. Feitosa, Claudia do Ó Pessoa
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2012-06-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
Online Access:http://orbital.ufms.br/index.php/Chemistry/article/view/371