Oral Glutamine Supplementation Reduces Obesity, Pro-Inflammatory Markers, and Improves Insulin Sensitivity in DIO Wistar Rats and Reduces Waist Circumference in Overweight and Obese Humans

Oral Glutamine Supplementation Reduces Obesity, Pro-Inflammatory Markers, and Improves Insulin Sensitivity in DIO Wistar Rats and Reduces Waist Circumference in Overweight and Obese Humans

In the present study, we aimed to investigate whether chronic oral glutamine (Gln) supplementation may alter metabolic parameters and the inflammatory profile in overweight and obese humans as well as whether Gln may modulate molecular pathways in key tissues linked to the insulin action in rats. Th...

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Bibliographic Details
Main Authors: Kahlile Youssef Abboud, Sabrina Karen Reis, Maria Eduarda Martelli, Olivia Pizetta Zordão, Fabiana Tannihão, Alessandra Zanin Zambom de Souza, Heloisa Balan Assalin, Dioze Guadagnini, Guilherme Zweig Rocha, Mario Jose Abdalla Saad, Patricia Oliveira Prada
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Nutrients
Subjects:
obesity
glutamine supplementation
inflammation
insulin sensitivity
cytokines
clamp
LPS
hexosamine
Online Access:http://www.mdpi.com/2072-6643/11/3/536

Internet

http://www.mdpi.com/2072-6643/11/3/536

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