Inotuzumab ozogamicin in clinical development for acute lymphoblastic leukemia and non-Hodgkin lymphoma

Abstract B cell acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) frequently express CD19, CD20 and CD22 on the cell surfaces. Immunotherapeutic agents including antibodies and chimeric antigen receptor T cells are widely studied in clinical trials. Several antibody-drug conjugates (...

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Bibliographic Details
Main Authors: Amandeep Aujla, Ravijot Aujla, Delong Liu
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Biomarker Research
Subjects:
ADC
Online Access:http://link.springer.com/article/10.1186/s40364-019-0160-4