Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice

Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice

Abstract Backgroud The regenerative capacity of the liver is crucial for the host to survive after serious hepatic injuries, tumor resection, or living donor liver transplantation. Panax notoginseng saponins (PNS) have been reported to exert protective effects during organ injuries. The present stud...

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Bibliographic Details
Main Authors: Hua Zhong, Hao Wu, He Bai, Menghao Wang, Jian Wen, Jianping Gong, Mingyong Miao, Fangchao Yuan
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Panax notoginseng saponins
Liver regeneration
Protein kinase B
Mammalian target of rapamycin
Online Access:http://link.springer.com/article/10.1186/s12906-019-2536-2

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http://link.springer.com/article/10.1186/s12906-019-2536-2

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