Influence of major structural features of tocopherols and tocotrienols on their ω-oxidation by tocopherol-ω-hydroxylase
Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial ω-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E. The objective of this study was to characterize this activity, particularly the inf...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2007-05-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520435552 |