Strong Association of the Myriad Discrete Speckled Nuclear Pattern With Anti-SS-A/Ro60 Antibodies: Consensus Experience of Four International Expert Centers

Strong Association of the Myriad Discrete Speckled Nuclear Pattern With Anti-SS-A/Ro60 Antibodies: Consensus Experience of Four International Expert Centers

IntroductionThe morphological patterns in indirect immunofluorescence assay on HEp-2 cells (HEp-2 IFA) reflect the autoantibodies in the sample. The International Consensus on ANA Patterns (ICAP) classifies 30 relevant patterns (AC-0 to AC-29). AC-4 (fine speckled nuclear pattern) is associated to a...

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Bibliographic Details
Main Authors: Nadja Röber, Alessandra Dellavance, Fernanda Ingénito, Marie-Luise Reimer, Orlando Gabriel Carballo, Karsten Conrad, Edward K. L. Chan, Luis E. C. Andrade
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
autoantibodies
antinuclear antibodies
SS-A/Ro antibodies
autoimmune disease
immunofluorescence patterns
HEp-2 cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.730102/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.730102/full

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