A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

Long non coding RNA molecules have been implicated in the immunopathology of a range of inflammatory pathologies. Here the authors show lncRNA MAARS regulates apoptosis via interaction with HuR in the context of atherosclerosis.

Bibliographic Details
Main Authors: Viorel Simion, Haoyang Zhou, Stefan Haemmig, Jacob B. Pierce, Shanelle Mendes, Yevgenia Tesmenitsky, Daniel Pérez-Cremades, James F. Lee, Alex F. Chen, Nicoletta Ronda, Bianca Papotti, Jarrod A. Marto, Mark W. Feinberg
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19664-2

Internet

https://doi.org/10.1038/s41467-020-19664-2

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