Partial restoration of macrophage alteration from diet-induced obesity in response to Porphyromonas gingivalis infection.

Obesity is a chronic inflammatory disease that weakens macrophage innate immune response to infections. Since M1 polarization is crucial during acute infectious diseases, we hypothesized that diet-induced obesity inhibits M1 polarization of macrophages in the response to bacterial infections. Bone m...

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Bibliographic Details
Main Authors: Guilhem Richard, Niraj Trivedi, Calin Belta, Salomon Amar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726386?pdf=render